![]() Blue indicates lymphatic vessels and organs that are closest to the camera, while yellow marks ones that are deeper inside the body. The wildDISCO imaging technique turns a mouse’s lymphatic system into a kaleidoscope of blues and yellows. ![]() Computational simulations of biology may help researchers move away from doing animal experiments, he says. The algorithms would aim, for example, to simulate how a drug travels through blood vessels, or predict the path of genetically engineered immune cells for cancer therapy, Ertürk says ( SN: 2/2/22). Such maps could help researchers train artificial intelligence programs to simulate bodily processes in mice. But in place of cars driving around to record every street, antibodies act as streetlamps to illuminate scientific landmarks. It’s a bit like Google Maps, says Ali Ertürk, a neuroscientist at Helmholtz Munich. ![]() The technique, dubbed wildDISCO, gives scientists an extraordinarily thorough peek under mouse skin to create body-wide anatomical atlases. ![]()
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